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Published Studies

Machado et al. (2016)

Kinley et al. (2020)

  • Design:
    Freeze dried Asparagopsis meal incubated in rumen for 72 h with Rhodes grass hay.

  • Test Article Conc.:
    0, 1, 5, 10, or 25 µM bromoform
    2% OM freeze-dried Asparagopsis (1.3 µM bromoform)

  • Findings:
    Bromoform: 1 µM ↓ CH₄ 43–52%
    ≥5 µM ↓ CH₄ 99%
    Asparagopsis: 1 µM ↓ CH₄ 95%

  • Design:
    Beef steers (n = 20; 4 groups of 5)
    Asparagopsis meal gradually introduced in TMR over 30 days, then maintained for 60 days

  • Test Article Conc.:
    Freeze-dried Asparagopsis meal
    (0, 6, 12, 24 mg bromoform/kg feed)

  • Findings:
    Concentration-related CH₄ ↓
    9%, 38%, and 98% reduction vs control

Kinley et al. (2016)

Roque et al. (2021)

  • Design:
    Freeze-dried Asparagopsis meal incubated in rumen for 72 h with Rhodes grass hay. Analysis at 12, 24, 36, 48, 72 h.

  • Test Article Conc.:
    1.0 g (OM) Rhodes grass and 0, 0.5, 1, 2, 5, or 10% Asparagopsis meal

  • Findings:
    Time- and concentration-related CH₄ ↓
    ↓ with ≥2% OM inclusion without negative effects on digestibility or fermentation

  • Design:
    Beef steers (n = 20; groups of 7, 7, and 6)
    21-week TMR feeding with data collection every 3 weeks
    Total exposure: 147 days

  • Test Article Conc.:
    Freeze-dried Asparagopsis meal
    (0, 36, 72 mg bromoform/kg feed)

  • Findings:
    Concentration-related CH₄ ↓ (up to 80%)
    Greater methane reduction in low-forage TMR vs high-forage

Chagas et al. (2019)

Cowley et al. (2024)

  • Design:
    Asparagopsis meal added to Timothy grass, rolled barley, and canola meal in rumen fluid and incubated 48 h

  • Test Article Conc.:
    Asparagopsis meal (0, 0.06, 0.23, 0.25, 0.5, or 1.0 g/kg diet OM)

  • Findings:
    Time- and concentration-related CH₄ ↓

  • Design:
    Beef steers (n = 18; groups of 4, 5, 5, 4)
    Gradual introduction over 21 days + 56-day treatment
    Weekly data collection

  • Test Article Conc.:
    Asparagopsis oil
    (0, 17, 34, 51 mg bromoform/kg feed)

  • Findings:
    Concentration-related CH₄ ↓
    Up to 99% reduction

Kinley et al. (2021)

  • Design:
    Asparagopsis meal added to several diets with varying grass:grain ratios and incubated for 24, 48, and 72 h

  • Test Article Conc.:
    Asparagopsis meal (50, 80, 110, 140, and 160 mg bromoform/kg DM)

  • Findings:
    More effective in high-grain diets
    Can reach ~99% CH₄ reduction at higher concentrations

Roque et al. (2019)

  • Design:
    Dairy cows (n = 12; 3 groups of 4)
    TMR feeding with 3 × 3 Latin square design
    3 experimental periods of 14 days

  • Test Article Conc.:
    Freeze-dried Asparagopsis meal
    (0, 12, 24 mg bromoform/kg feed)

  • Findings:
    Concentration-related CH₄ ↓
    Up to 67% reduction

Kinley et al. (2022)

  • Design:
    Asparagopsis meal vs Asparagopsis oil added to Rhodes grass hay and incubated for 24, 48, and 72 h

  • Test Article Conc.:
    Meal (95, 190, 286 mg bromoform/kg DM)
    Oil (78, 117, 175 mg bromoform/kg DM)

  • Findings:
    Oil as effective as meal
    CH₄ ↓ without negative effects on digestibility or fermentation

Stefenoni et al. (2021)

  • Design:
    Dairy cows (n = 20; 4 groups of 4)
    4 × 4 Latin square design
    28-day periods (21-day adaptation + 7-day sampling)

  • Test Article Conc.:
    0, 0.25, or 0.5% freeze-dried Asparagopsis meal (DM basis)
    Bromoform level unknown

  • Findings:
    CH₄ ↓ up to 80%
    (0.5% Asparagopsis group)

Alvarez-Hess et al. (2023)

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  • Design:
    Dairy cows (n = 39; 3 groups of 13)
    Feeding twice daily in milking system over 32 days

  • Test Article Conc.:
    Asparagopsis oil with & without seaweed biomass
    (0 or 16.7 mg bromoform/kg feed)

  • Findings:
    CH₄ ↓ up to 42%
    (Asparagopsis oil without biomass)

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